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α-Carbalkoxylations of carboxylic acids. A general synthetic route to monoesters of malonic acids.

✍ Scribed by A.Paul Krapcho; Edwin G.E. Jahngen Jr.; David S. Kashdan


Publisher
Elsevier Science
Year
1974
Tongue
French
Weight
136 KB
Volume
15
Category
Article
ISSN
0040-4039

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Carboxylic acids were conveniently esterfied with alcohols and thiols by the use of triphenylphosphine and N-bromo/Iodo succinimide to afford the corresponding esters and thiol esters. Conversion of carboxylic acids to their corresponding esters and thiol esters is a well established fundamental org