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A new approach to α-methylene-γ-butyrolactones. II. Synthesis of (+)-arbusculin-B

✍ Scribed by A.E. Greene; J.-C. Muller; G. Ourisson


Publisher
Elsevier Science
Year
1972
Tongue
French
Weight
183 KB
Volume
13
Category
Article
ISSN
0040-4039

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Enantioselective synthesis of α-methylen
✍ Chinnasamy Muthiah; Midori A. Arai; Toshio Shinohara; Takayoshi Arai; Shinobu Ta 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 186 KB

Combination of Pd(OCOCF 3 ) 2 and (M,S,S)-iPr-SPRIX ligand promoted the intramolecular cyclization of 2-alkynoates very effectively to form a-methylene-g-butyrolactones in good yields with up to 92% ee.