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ChemInform Abstract: The Renaissance of α-Methylene-γ-butyrolactones: New Synthetic Approaches

✍ Scribed by Russell R. A. Kitson; Alessia Millemaggi; Richard J. K. Taylor

Publisher
John Wiley and Sons
Year
2010
Weight
17 KB
Volume
41
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Preparation of α-Me
ChemInform Abstract: Preparation of α-Methylene-γ-butyrolactones with Difluoromethylene Functionalities.
✍ H. FUKUDA; T. KITAZUME 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB 👁 1 views

Preparation of α-Methylene-γ-butyrolactones with Difluoromethylene Functionalities. -The key to the preparation of title compounds such as (XII), of interest as pharmaceutical drugs, is the regioselective reduction of the ester group of compound (VI) activated with a difluoromethylene unit to give