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A natural histone deacetylase inhibitor, Psammaplin A, induces cell cycle arrest and apoptosis in human endometrial cancer cells

โœ Scribed by Mee Young Ahn; Jee H. Jung; Yong Jin Na; Hyung Sik Kim


Book ID
113961353
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
863 KB
Volume
108
Category
Article
ISSN
0090-8258

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## Abstract Remodeling of the chromatin template by inhibition of HDAC activities represents a potential transcriptional therapy for neoplastic disease. A number of HDAC inhibitors that modulate __in vitro__ cell growth and differentiation have been developed. We analyzed the effects of TSA, a spec