Histone deacetylase inhibitor trichostat
β
Yo-ichi Yamashita; Mitsuo Shimada; Norifumi Harimoto; Tatsuya Rikimaru; Ken Shir
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Article
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2002
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John Wiley and Sons
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French
β 212 KB
π 1 views
## Abstract Remodeling of the chromatin template by inhibition of HDAC activities represents a potential transcriptional therapy for neoplastic disease. A number of HDAC inhibitors that modulate __in vitro__ cell growth and differentiation have been developed. We analyzed the effects of TSA, a spec