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Histone deacetylase inhibitors trichostatin A and valproic acid circumvent apoptosis in human leukemic cells expressing the RUNX1 chimera

✍ Scribed by Ko Sasaki; Tetsuya Yamagata; Kinuko Mitani


Book ID
108584091
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
422 KB
Volume
99
Category
Article
ISSN
1347-9032

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## Abstract Aberrant janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling is involved in the oncogenesis of several cancers. Suppressors of cytokine signaling (SOCS) genes and SH2‐containing protein tyrosine phosphatase 1 (SHP1) proteins, which are negative regulator