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A mild and efficient synthesis of intermediates for the Pomeranz-Fritsch reaction

✍ Scribed by Alan R. Katritzky; Zhijun Yang; Darren J. Cundy

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
311 KB
Volume
5
Category
Article
ISSN
1042-7163

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✦ Synopsis

Reaction of I-chlon~-2,2-dimethoxyethane with sodium azide affords l -azido-2,2-dimethoxyethane which, upon treatment with triphenylphosphine followed by aromatic aldehydes, alkyl bromides, or isocyanates, gives the corresponding dimethyl a-arylimino-, a-alkylamino-, and a-carbodiimido-acetals, respectively, in good to excellent yields.

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Synthesis of the Carbon Framework of the Stephaoxocanes Employing a Sequential RCM/Pomeranz–Fritsch Approach
✍ Andrea B. J. Bracca; Teodoro S. Kaufman πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 218 KB

## Abstract The syntheses of two cyclodeca[__ij__]isoquinoline derivatives, which embody the carbon framework of stephaoxocanidine, excentricine and the recently isolated stephalonganines A, B and C, are reported. The target tricyclic compounds were prepared from isovanillin, employing a ring‐closi