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A LOW DOSE OF STREPTOZOTOCIN PREVENTS KAINIC ACID-INDUCED SEIZURES AND LETHAL EFFECTS IN THE RAT

โœ Scribed by Hyoung-Chun Kim; Doo-Hyun Im; Wang-Kee Jhoo; Chin Kim; Myung-Bok Wie


Book ID
108937069
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
259 KB
Volume
24
Category
Article
ISSN
0305-1870

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Seizure activity induced by kainic acid (KA) and subsequent neuronal death are thought to be associated with an increase in cytoplasmic free calcium ([Ca2+li) and can be prevented by N-methyl-D-aspartate (NMDA) antagonists. In addition to influx through receptor operated Ca2+ channels the increase i