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A single oral dose of geranylgeranylacetone attenuates kainic acid-induced seizures and neuronal cell death in rat hippocampus

✍ Scribed by Minoru Fujiki; Hidenori Kobayashi; Ryo Inoue; Keisuke Ishii


Book ID
113499936
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
345 KB
Volume
1021
Category
Article
ISSN
0006-8993

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## Abstract Recent studies have shown that ethyl pyruvate (EP) acts as an anti‐inflammatory molecule in several cell lines including RAW264.7 macrophages. However, the potential therapeutic value of EP for the treatment of the pathologic brain has not been investigated fully. In the present study,