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Kainic Acid-Induced Seizures and Brain Damage in the Rat: Different Effects of NMDA- and AMPA Receptor Antagonists

✍ Scribed by Berg, M. ;Bruhn, T. ;Johansen, F. F. ;Diemer, N. H.

Book ID
114801942
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
920 KB
Volume
73
Category
Article
ISSN
0901-9928

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Kainic acid-induced seizures and brain d
Kainic acid-induced seizures and brain damage in the rat: Role of calcium homeostasis
✍ M. Berg; T. Bruhn; Aa. Frandsen; A. Schousboe; N. H. Diemer πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 901 KB

Seizure activity induced by kainic acid (KA) and subsequent neuronal death are thought to be associated with an increase in cytoplasmic free calcium ([Ca2+li) and can be prevented by N-methyl-D-aspartate (NMDA) antagonists. In addition to influx through receptor operated Ca2+ channels the increase i