Brain distribution and efficacy of carbamazepine in kainic acid induced seizure in rats
โ Scribed by Li Wang; Chi-hua Zuo; Da-yao Zhao; Xi-ru Wu
- Book ID
- 117545300
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 78 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0387-7604
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Seizure activity induced by kainic acid (KA) and subsequent neuronal death are thought to be associated with an increase in cytoplasmic free calcium ([Ca2+li) and can be prevented by N-methyl-D-aspartate (NMDA) antagonists. In addition to influx through receptor operated Ca2+ channels the increase i
This study reports comparative dose-response data for kainic acid (KA) induced seizures in juvenile (35-40 days old) and adult (70-90 days old) Wistar-Furth (WF), Fisher 344 (F344), Sprague-Dawley (SD) and Long-Evans Hooded (LEH) rats. Juvenile male WF (n = 51), F344 (n = 55), SD (n = 60), LEH (n =