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Inhibition of kainic acid induced expression of interleukin-1β and interleukin-1 receptor antagonist mRNA in the rat brain by NMDA receptor antagonists

✍ Scribed by Charlotta Eriksson; Li-Ping Zou; Sven Ahlenius; Bengt Winblad; Marianne Schultzberg


Book ID
117385587
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
807 KB
Volume
85
Category
Article
ISSN
0169-328X

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✍ Charlotta Eriksson; Roya Tehranian; Kerstin Iverfeldt; Bengt Winblad; Marianne S 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 427 KB 👁 1 views

Kainic acid, an analogue of glutamate, injected systemically to rats evokes seizures that are accompanied by nerve cell damage primarily in the limbic system. In the present study, we have analyzed the temporal profile of the expression of the cytokines interleukin-1␤ (IL-1␤) and IL-1 receptor antag