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A High-Throughput Screening Protocol for Fast Evaluation of Enantioselective Catalysts

✍ Scribed by Wolf, Christian; Hawes, Pili A.

Book ID
120268794
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
42 KB
Volume
67
Category
Article
ISSN
0022-3263

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πŸ“œ SIMILAR VOLUMES

A Method for High-Throughput Screening o
A Method for High-Throughput Screening of Enantioselective Catalysts
✍ Manfred T. Reetz; Michael H. Becker; Heinz-Werner Klein; Detlef StΓΆckigt πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 119 KB πŸ‘ 2 views

About 1000 catalytic or stoichiometric asymmetric reactions of racemic compounds or prochiral substrates bearing enantiotopic groups can be analyzed per day. In this highly efficient method the enantioselectivity is determined by electrospray ionization mass spectrometry using isotopically labeled s

A Practical NMR-Based High-Throughput As
A Practical NMR-Based High-Throughput Assay for Screening Enantioselective Catalysts and Biocatalysts
✍ Manfredβ€…T. Reetz; Andreas Eipper; Patrick Tielmann; Richard Mynott πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 148 KB πŸ‘ 2 views

Two NMR-based approaches for highthroughput screening of enantioselective catalysts and biocatalysts are described. One version makes use of pseudo-enantiomers or pseudo-meso-compounds based on 13 C-labeling. A throughput of at least 1400 ee determinations per day is possible by using an appropriate