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A High-Throughput-Screening Method for Determining the Synthetic Activity of Hydrolases

✍ Scribed by Monika Konarzycka-Bessler; Uwe T. Bornscheuer

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
111 KB
Volume
42
Category
Article
ISSN
0044-8249

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A Method for High-Throughput Screening of Enantioselective Catalysts
✍ Manfred T. Reetz; Michael H. Becker; Heinz-Werner Klein; Detlef StΓΆckigt πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 119 KB πŸ‘ 2 views

About 1000 catalytic or stoichiometric asymmetric reactions of racemic compounds or prochiral substrates bearing enantiotopic groups can be analyzed per day. In this highly efficient method the enantioselectivity is determined by electrospray ionization mass spectrometry using isotopically labeled s