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A functional role of the cyclin-dependent kinase inhibitor 1 (p21WAF1/CIP1) for neuronal preconditioning

✍ Scribed by Mergenthaler, Philipp; Muselmann, Claudia; Sünwoldt, Juliane; Isaev, Nickolay K; Wieloch, Tadeusz; Dirnagl, Ulrich; Meisel, Andreas; Ruscher, Karsten


Book ID
120053630
Publisher
Nature Publishing Group
Year
2013
Tongue
English
Weight
309 KB
Volume
33
Category
Article
ISSN
0271-678X

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Regulation of cyclin-dependent kinase in
✍ J H Albrecht; A H Meyer; M Y Hu 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 817 KB

WAF1/Cip1/Sdi1 (p21) is the prototype of a family of proteins that inhibit cyclin-dependent kinases and regulate cell cycle progression in eukaryotic cells. In addition to normal cell cycle progression, p21 is involved in growth suppression mediated by p53 and transforming growth factor beta (TGFbet