A Facile Preparation of (.+-.)-β-Hydroxy Nitriles and Their Enzymatic Resolution with Lipases.

A New Route to Protected Acyloins and Th

A New Route to Protected Acyloins and Their Enzymatic Resolution with Lipases

✍ Günther Scheid; Wouter Kuit; Eelco Ruijter; Romano V. A. Orru; Erik Henke; Uwe B 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 201 KB

Efficient Lipase-Catalyzed Kinetic Resol

Efficient Lipase-Catalyzed Kinetic Resolution and Dynamic Kinetic Resolution of β-Hydroxy Nitriles. Correction of Absolute Configuration and Transformation to Chiral β-Hydroxy Acids and γ-Amino Alcohols

✍ Oscar Pàmies; Jan-E. Bäckvall 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 87 KB 👁 1 views

Chemoenzymatic dynamic kinetic resolution of b-hydroxy nitriles 1 has been carried out using Candida antarctica lipase B and a ruthenium catalyst. The use of a hydrogen source to depress ketone formation in the dynamic kinetic resolution yields the corresponding acetates 2 in good yield and high ena

Efficient Lipase-Catalyzed Kinetic Resol

Efficient Lipase-Catalyzed Kinetic Resolution and Dynamic Kinetic Resolution of β-Hydroxy Nitriles. Correction of Absolute Configuration and Transformation to Chiral β-Hydroxy Acids and γ-Amino Alcohols.

✍ Oscar Pamies; Jan-E. Baeckvall 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 344 KB 👁 1 views

Efficient Lipase-Catalyzed Kinetic Resol

Efficient Lipase-Catalyzed Kinetic Resolution and Dynamic Kinetic Resolution of β-Hydroxy Nitriles. A Route to Useful Precursors for γ-Amino Alcohols

✍ Oscar Pàmies; Jan-E. Bäckvall 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 97 KB 👁 1 views

Facile conversion of epoxides to β-hydro

Facile conversion of epoxides to β-hydroxy nitriles under anhydrous conditions with lithium cyanide

✍ James A. Ciaccio; Catherine Stanescu; Jongnic Bontemps 📂 Article 📅 1992 🏛 Elsevier Science 🌐 French ⚖ 236 KB

Functionalir@d epoxides are easily and efficiently converted lo P-hydroxy nitnles In good yield with high fegio-and stereoselectivity upon treatment with lithium cyanide in rcfluxing anhydrous THF The conditions described permit a one-pot conversion of epoxide to 1 J-amino alcohol via hydnde reducti

ChemInform Abstract: Efficient Lipase-Ca

ChemInform Abstract: Efficient Lipase-Catalyzed Kinetic Resolution and Dynamic Kinetic Resolution of β-Hydroxy Nitriles. A Route to Useful Precursors for γ-Amino Alcohols.

✍ Oscar Pamies; Jan-E. Baeckvall 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

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