A Facile and Novel Route to the Antigenic Branched Phosphoglycan of the Protozoan Leishmania major Parasite.

Parasite dose determines the Th1/Th2 nat

Parasite dose determines the Th1/Th2 nature of the response to Leishmania major independently of infection route and strain of host or parasite

✍ Juthika N. Menon; Peter A. Bretscher 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 126 KB

A facile synthetic route to the 14C-labe

A facile synthetic route to the 14C-labeled enantiomers of MK-196, A new uricosuric diuretic, and its major metabolite

✍ Otto W. Woltersdorf Jr. 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 French ⚖ 217 KB

## Abstract The enantiomers of MK‐196, (6,7‐dichloro‐2‐methyl‐1‐oxo‐2‐phenyl‐5‐indanyloxy)‐acetic acid, and the 2‐(4‐hydroxyphenyl) derivative, the major metabolite of MK‐196, were resolved by classical methods using α‐methylbenzylamine salts, and converted to the corresponding, enantiomerically pu

[4+2]-Cycloadditions of Azoalkenes to Az

[4+2]-Cycloadditions of Azoalkenes to Azodicarbonyl Compounds. A Novel Facile Route to the 1,2,3,4-Tetrazine System

✍ Dr. Sven Sommer; Dr. Ulrich Schubert 📂 Article 📅 1979 🏛 John Wiley and Sons 🌐 English ⚖ 228 KB 👁 2 views

A Facile Route to the Synthesis of Novel

A Facile Route to the Synthesis of Novel 2-Amino-1,4,5,6-tetrahydropyrimidines from Baylis—Hillman Products of Acrylonitrile.

✍ Richa Pathak; Amrendra K. Roy; Sanjay Batra 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 22 KB 👁 1 views

The Nonchiral Bislactim Diethoxy Ether a

The Nonchiral Bislactim Diethoxy Ether as a Highly Stereo-Inducing Synthon for Sterically Hindered, γ-Branched α-Amino Acids: A Practical, Large-Scale Route to an Intermediate of the Novel Renin Inhibitor Aliskiren.

✍ Richard Goeschke; Stefan Stutz; Walter Heinzelmann; Juergen Maibaum 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 143 KB

The Nonchiral Bislactim Diethoxy Ether a

The Nonchiral Bislactim Diethoxy Ether as a Highly Stereo-Inducing Synthon for Sterically Hindered, γ-Branched α-Amino Acids: A Practical, Large-Scale Route to an Intermediate of the Novel Renin Inhibitor Aliskiren

✍ Richard Göschke; Stefan Stutz; Walter Heinzelmann; Jürgen Maibaum 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 German ⚖ 327 KB

## Abstract The diastereoselective synthesis of the sterically hindered, __γ__‐branched __α__‐amino acid derivative (2__S__,4__S__)‐**24a** and its __N__‐[(__tert__‐butoxy)carbonyl](Boc)‐protected alcohol (2__S__,4__S__)‐**19**, both key intermediates of a novel class of nonpeptide renin inhibitors