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A convenient synthesis of 13C-bromoform and 13C-tetrabromomethane from 13C-iodomethane labelling through 13:CBr2

✍ Scribed by Herbert Siegel; Dieter Seebach

Publisher
John Wiley and Sons
Year
1980
Tongue
French
Weight
299 KB
Volume
17
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Phenyldithiane 3 is methylated with ^13^CH~3~I to give, through the thioacetal 4, labelled acetophenone (5). NaOBr‐cleavage to the title compounds 1 and 2 (65 % and 76 %, respectively) and their use in the preparation of the dibromocyclopropane 6 and the dibromoolefin 7 are described.

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