A convenient method for the synthesis of 2-trichloromethyl-4-p-substituted-phenyl-3h-1,5-benzodiazepines
✍ Scribed by Helio G. Bonacorso; Sandra T. Bittencourt; Arci D. Wastowski; Alexandre P. Wentz; Nilo Zanatta; A.P. Marcos; Martins
- Book ID
- 104255930
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 123 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
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## Abstract The preparation of eight novel substituted [1,2,4]oxadiazolo[4,5‐__a__][1,5]benzodiazepines which have potentially useful pharmacological properties; by 1,3‐cycloaddition of benzonitrile oxides, generated __in situ__ from benzohydroxamoyl chloride and triethylamine, to 1,5‐benzodiazepin
## Abstract A series of eleven new 2‐methylthio‐3__H__‐7‐[(__o__‐; __m__‐ and __p__‐substituted) phenoxy]‐4‐(__p__‐substituted‐phenyl)‐[1,5]benzodiazepines, which have potentially useful pharmacological activities, has been synthesized by condensing the 4‐[(__o__‐; __m__‐ and __p__‐R~1~)phenoxy]‐1,
## Abstract A series of twelve new 2‐methylthio‐3__H__‐4‐(__p__‐substituted phenyl)‐7‐[(__o__‐, and __p__‐substituted)phenylthio]‐1,5‐benzodiazepines, which have potentially useful pharmacological properties, has been synthesized by condensing the 3,3‐dimercapto‐1‐(__para__‐substituted‐phenyl)‐2‐pr