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A convenient and inexpensive synthesis of labelled methylmalonic and propionic acids: application to the synthesis of methyl-d3-malonic and of propionic-3,3,3-d3 acids

✍ Scribed by Pietro Allevi; Alessandra Longo; Mario Anastasia


Publisher
John Wiley and Sons
Year
1999
Tongue
French
Weight
159 KB
Volume
42
Category
Article
ISSN
0022-2135

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Synthesis of [3-D3]-, [3-13C]-, and [1,2
✍ Claude Boullais; Christelle Rannou; Emmanuel RΓ©veillΓ¨re; Charles Mioskowski πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 242 KB πŸ‘ 1 views

Three selectively labeled propynes were prepared either with deuterium or carbon-13 at position 3 and doubly labeled with carbon-13 at positions 1 and 2 by an alkylation reaction from the corresponding labeled or unlabeled monolithio acetylides and dimethylsulfates. Their lithiation with nBuLi gave