𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A concise access to a new class of selective anti-inflammatory steroid derivatives

✍ Scribed by Béatrice Quiclet-Sire; Samir Z. Zard

Book ID
108386481
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
135 KB
Volume
39
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

9-pyridylidenefluorenes, a new class of
9-pyridylidenefluorenes, a new class of anti-inflammatory substances
✍ N. P. Buu-Hoï; F. Delbarre; P. Jacquignon; H. Brouilhet; A. Rose; J. F. Sabathie 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 163 KB

## Abstract The condensation of fluorene with the three formylpyridines and 2‐formyl‐6‐methylpyridine has been investigated, and the 9‐pyridylidenefluorenes obtained have been tested in rats for anti‐inflammatory activity. 9‐(3‐Pyridylidene)fluorene proved the most potent compound, with an activity

Synthetic studies towards ML-3000 a conc
Synthetic studies towards ML-3000 a concise synthesis of this non-steroidal anti-inflammatory drug
✍ Janine Cossy; Damien Belotti 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 625 KB

ML-3000 was obtained from l-chloro-3-phenyl-2-propyne in 8 steps with an overall yield of 19%. The key steps are a thermal acid-promoted bicyclization of an ¢o-acetylenic amino ester and a Suzuki cross-coupling reaction between a heteroaryl triflate and (4-chlorophenyl)boronic acid.

Synthesis and Anti-inflammatory Evaluati
Synthesis and Anti-inflammatory Evaluation of New Sulfamoylheterocarboxylic Derivatives
✍ Juan A. Díaz; M. Esther Morante; Salvador Vega; Victoriano Darias; Susana Abdala 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 761 KB

A series of ReW sulfamoylthiophene and sulfamoytpyrazole carboxylic acid derivatives was synthesized. Some of these compounds show interesting analgesic properties and significant nonsteroidal anti-inflammatov activities in several models of inflammation.