Synthesis and Anti-inflammatory Evaluation of New Sulfamoylheterocarboxylic Derivatives
✍ Scribed by Juan A. Díaz; M. Esther Morante; Salvador Vega; Victoriano Darias; Susana Abdala; Laura Delgado; Beatriz de las Heras; Angel Villar; José María Vivas
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 761 KB
- Volume
- 329
- Category
- Article
- ISSN
- 0365-6233
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✦ Synopsis
A series of ReW sulfamoylthiophene and sulfamoytpyrazole carboxylic acid derivatives was synthesized. Some of these compounds show interesting analgesic properties and significant nonsteroidal anti-inflammatov activities in several models of inflammation.
📜 SIMILAR VOLUMES
The role of reactive oxygen species in inflammatory processes has been well documented, while several antioxidant compounds have been shown to exhibit anti-inflammatory activity. We designed novel compounds as potential agents that combine enhanced antioxidant and anti-inflammatory activities. Deriv