๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

A compartment model for percutaneous drug absorption

โœ Scribed by Kiyoshi Kubota

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
281 KB
Volume
80
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

A compartment model for percutaneous abs
A compartment model for percutaneous absorption: Compatibility of lag time and steady-state flux with diffusion model
โœ Kiyoshi Kubota; Howard I. Maibach ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 305 KB

The lag times and steady-state flux predicted by a specific case of the compartment model, which was recently proposed to generate finite-dose percutaneous permeation pharmacokinetics, are compared with those predicted by the diffusion model. When the intercompartmental transfer rate constants are d

Percutaneous absorption of trinitrobenze
Percutaneous absorption of trinitrobenzene: animal models for human skin
โœ Margaret E. K. Kraeling; Gunda Reddy; Robert L. Bronaugh ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 65 KB ๐Ÿ‘ 2 views

The percutaneous absorption of 1,3,5-trinitrobenzene (TNB) was studied in viable skin from hairless guinea pigs (HGP), Fischer 344 rats and humans. Skin was dermatomed and assembled in flow-through diffusion cells followed by TNB application in either an acetone or a water vehicle. Skin absorption w

Oral and IV dosing: A method to determin
Oral and IV dosing: A method to determine the compartment of drug elimination for two-compartment models
โœ J.W.T. Yates; P.A. Arundel ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 91 KB

It has been shown previously that it is impossible to measure the volume of distribution at steady state conclusively for a multicompartment system from an iv bolus dose only. The problem lies in deciding from which compartment elimination of the drug occurs in the compartmental model. In this paper