The aim of this study was to predict the disposition of midazolam in individual surgical patients by physiologically based pharmacokinetic (PBPK) modeling and explore the causes of interindividual variability. Tissueยฑplasma partition coefยฎcients (k p ) were scaled from rat to human values by a physi
A pharmacokinetic model for the percutaneous absorption of indomethacin and the prediction of drug disposition kinetics
โ Scribed by Taro Ogiso; Yoshimasa Ito; Masahiro Iwaki; Hidehiko Atago
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 497 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0022-3549
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