𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A comparison of the binding and distribution of benzo[a]pyrene in human and rat serum

✍ Scribed by Kjell Aarstad; Rune Toftgård; Odd G. Nilsen

Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
489 KB
Volume
47
Category
Article
ISSN
0300-483X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Distribution of benzo[a]pyrene in pregna
Distribution of benzo[a]pyrene in pregnant rats following inhalation exposure and a comparison with similar data obtained with pyrene
✍ J. R. Withey; J. Shedden; F. C. P. Law; S. Abedini 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 737 KB

Eight pregnant rats were exposed, on the 17th day of gestation, for 95 min to a microcondensation aerosol of benzo[a]pyrene at five different atmospheric concentrations between 200 and 800 mg m-3 in a 'head-only' inhalation chamber. Five rats were killed immediately following the exposure and three

Rat liver microsome-mediated binding of
Rat liver microsome-mediated binding of benzo(A)pyrene metabolites to DNA
✍ M. H. Thompson; H. W. S. King; M. R. Osborne; P. Brookes 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 French ⚖ 422 KB 👁 1 views

## Abstract Individual metabolites of benzo (a)pyrene were isolated from rat liver microsomal incubation of the parent hydrocarbon, and subsequently bound to DNA in separate incubations with microsomes. Of the metabolites examined, by far the greatest binding resulted with 7,8‐dihydro‐7,8‐dihydroxy

Excretion of 3-hydroxy-benzo(a)pyrene an
Excretion of 3-hydroxy-benzo(a)pyrene and mutagenicity in rat urine after exposure to benzo(a)pyrene
✍ F. J. Jongeneelen; Ch. M. Leijdekkers; R. P. Bos; J. L. G. Theuws; P. Th. Hender 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 463 KB 👁 1 views

3-hydroxy-benzo(a)pyrene (3-OH-B(a)P) and mutagenic activity in rat urine were determined after the oral administration of benzo(a)pyrene given in three repeated doses of 10, 20 and 50 pmol kg-'. The procedure for the determination of 3-OH-B(a)P consisted of enzymic hydrolysis, separation and HPLC-a

Metabolism and binding of benzo[a]pyrene
Metabolism and binding of benzo[a]pyrene in randomly-proliferating, confluent and s-phase human skin fibroblasts
✍ Mary Jane Cunningham; Ponnamma Kurian; George E. Milo 📂 Article 📅 1989 🏛 Springer 🌐 English ⚖ 886 KB

role in the expression of a transformed phenotype and that metabolism and transformation are not directly related. Furthermore, confluent dense cultures with a heightened capability for metabolism of benzo[a~yrene were more active in the detoxification of benzo[a~oyrene than in the production of the