## Abstract The macrocyclic lactone (__S__)βcurvularin (10) and its enantiomer __ent__β10 were prepared in an enantiodivergent manner from (__S__)βmethyl 7βhydroxyoctanoate (4), which was easily obtained on two different ways. Esterification of 4 under either retention or inversion of the chiral ce
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A Chemoenzymatic Synthesis of The Macrocyclic Lactone (S)-Curvularin
β Scribed by Bracher, Franz ;Schulte, Brigitte
- Book ID
- 120316349
- Publisher
- Taylor and Francis Group
- Year
- 1995
- Tongue
- English
- Weight
- 245 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1057-5634
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An Enantiodivergent Synthesis of Both Enantiomers of the Macrocyclic Lactone Curvularin. -An enantiodivergent synthesis of curvularin (S)-(IX) and its enantiomer is presented based on the esterification of key intermediate (S)-(V) under either retention or inversion of the chiral center leading to
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