A calorimetric study of the triple helix formation: Interaction of poly(C) · guanosine · protonated poly(C)
✍ Scribed by H. Klump
- Book ID
- 115746082
- Publisher
- Elsevier Science
- Year
- 1975
- Weight
- 313 KB
- Volume
- 383
- Category
- Article
- ISSN
- 0005-2787
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📜 SIMILAR VOLUMES
## Abstract Apparent second‐order rate constants for complex formation between poly (I) and poly (C) and copolymers of C containing non‐complementary I or U residues have been determined spectrophotometrically. The rate constants decrease as the concentration of either I or U in the C strands incre
The fixation of trans-(NH&Clz Pt(I1) to poly(1)-poly(C) a t low rb (<0.05) leads to the formation of two complexed species. The major species (ca. 82% of bound platinum) involves coordination of platinum to a single hypoxanthine base, while the other species involves coordination of two hypoxanthine
The fixation of cis(NH&C12Pt(II) to poly(1)-poly(C) leads to the formation of two complexed species. One involves coordination to a single base (accounting for about 70% of the total platinum bound over the Fb range 0.07-0.25) and the other to two bases which are not adjacent to each other but may b
## Abstract The slow kinetics of annealing processes in multistranded nucleic acids is spectrophotometrically investigated using poly(A)·2poly(U) as a model system. The absorbance changes at specific wavelengths show that double‐helical (A·U) base pairs appear as transient intermediates. The anneal