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995 Genes coding for tumor rejection antigens

✍ Scribed by T. Boon; P. Van Der Bruggen; V. Brichard; A. Van Pel; P.G. Coulie; B. Gaugler; B. Van Den Eynde; E. De Plaen


Book ID
116167739
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
315 KB
Volume
31
Category
Article
ISSN
0959-8049

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The human genes MAGE-I and -3 encode melanoma peptide antigens that are recognized by autologous cytotoxic T lymphocytes. Tumors expressing MAGE genes are potential targets for cancer immunotherapy, because MAGE genes are expressed only in tumor tissue and not in any normal tissue except testis and