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8,9-Dihydroxy-2,3,7,11b-tetrahydro-1 H -naph[1,2,3- de ]isoquinoline: A Potent Full Dopamine D 1 Agonist Containing a Rigid β-Phenyldopamine Pharmacophore

✍ Scribed by Ghosh, Debasis; Snyder, Scott E.; Watts, Val J.; Mailman, Richard B.; Nichols, David E.


Book ID
121881830
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
272 KB
Volume
39
Category
Article
ISSN
0022-2623

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ChemInform Abstract: Alternative Formal
✍ Amjad M. Qandil; Debasis Ghosh; David E. Nichols 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 2 views

Alternative Formal Synthesis of the Potent D 1 Dopamine Agonist 3,7,2,isoquinoline: Dinapsoline. -An alternative way to key intermediate (V), highly efficient for preparation of large quantities, improves the synthesis of dinapsoline (VI). Starting from commercially available benzyl alcohol (I), Su