Further Definition of the D 1 Dopamine Receptor Pharmacophore: Synthesis of trans -6,6a,7,8,9,13b-Hexahydro-5 H -benzo[ d ]naphth[2,1- b ]azepines as Rigid Analogues of β-Phenyldopamine

ChemInform Abstract: Further Definition

ChemInform Abstract: Further Definition of the D1 Dopamine Receptor Pharmacophore: Synthesis of trans-6,6a,7,8,9,13b-Hexahydro-5H-benzo(d)naphth(2,1-b) azepines as Rigid Analogues of β-Phenyldopamine.

✍ K. NEGASH; D. E. NICHOLS; V. J. WATTS; R. B. MAILMAN 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 2 views

Novel Stereoselective Syntheses of the F

Novel Stereoselective Syntheses of the Fused Benzazepine Dopamine D 1 Antagonist (6a S ,13b R )-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5 H - benzo[ d ]naphth[2,1- b ]azepin-12-ol (Sch 39166): 1. Aziridinium Salt Based Syntheses

✍ Draper, Richard W.; Hou, Donald; Iyer, Radha; Lee, Gary M.; Liang, Jimmy T.; Mas 📂 Article 📅 1998 🏛 American Chemical Society 🌐 English ⚖ 282 KB

Novel Stereoselective Syntheses of the F

Novel Stereoselective Syntheses of the Fused Benzazepine Dopamine D 1 Antagonist (6a S ,13 b R )-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl- 5 H -benzo[ d ]naphth[2,1- b ]azepin-12-ol (Sch 39166): 2. l -Homophenylalanine-Based Syntheses

✍ Draper, Richard W.; Hou, Donald; Iyer, Radha; Lee, Gary M.; Liang, Jimmy T.; Mas 📂 Article 📅 1998 🏛 American Chemical Society 🌐 English ⚖ 198 KB

ChemInform Abstract: Novel Stereoselecti

ChemInform Abstract: Novel Stereoselective Syntheses of the Fused Benzazepine Dopamine D1 Antagonist (6aS,13bR)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo [d]naphth[2,1-b]azepin-12-ol (Sch 39166). Part 1. Aziridinium Salt Based Syntheses.

✍ R. W. DRAPER; D. HOU; R. IYER; G. M. LEE; J. T. LIANG; J. L. MAS; W. TORMOS; E. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 43 KB 👁 1 views

ChemInform Abstract: Novel Stereoselecti

ChemInform Abstract: Novel Stereoselective Syntheses of the Fused Benzazepine Dopamine D1 Antagonist (6aS,13bR)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo [d]naphth[2,1-b]azepin-12-ol (Sch 39166). Part 2. L-Homophenylalanine-Based Syntheses.

✍ R. W. DRAPER; D. HOU; R. IYER; G. M. LEE; J. T. LIANG; J. L. MAS; E. J. VATER 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 44 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Total Synthesis of [3aS-(3aα,9aα,9bβ)]-3

Total Synthesis of [3aS-(3aα,9aα,9bβ)]-3a,4,5,9,9a,9b-Hexahydro-3a,6-dimethyl-1H-benz[e]indene-3,7(2H,8H)-dione and Derivatives, Building Blocks for the Synthesis of Glucocorticoids

✍ Daniewski, Andrzej Robert ;Piotrowska, Emilia ;Wojciechowska, Wanda 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 417 KB 👁 1 views

The natural and synthetic glucocorticoids are very important compounds commonly used as drugs against many diseases. Recently, we have reported the synthesis of some of the title compounds and their transformations into 6-methyl-5-androstene-3,11,17-trione 3-ethyleneacctal, a building block for the