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84: Effects of Lanthanum Carbonate on the Oral Absorption and Bioavailability of Ciprofloxacin

โœ Scribed by Priscilla How; James Fischer; Jose Arruda; Alan Lau

Book ID
114467837
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
178 KB
Volume
49
Category
Article
ISSN
0272-6386

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โœ Mohsen A. Hedaya; Dalia R. El-Afify; Gamal M. El-Maghraby ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 108 KB

Sildenafil is the first oral therapeutic agent for the management of male erectile dysfunction. Its oral bioavailability is only 40% due to extensive presystemic elimination, mainly by CYP3A4. This study examined the effect of coadministration of ciprofloxacin or clarithromycin, which inhibit CYP3A4