## Abstract Constitutive activation of the kinase cascade involving __RAS__, __RAF__, __MEK__ and __ERK__ is common to human cancers, and mutations of __KRAS__ and __BRAF__ are mutually exclusive and serve as alternatives to activate the RAS/RAF/ERK signaling pathway. __RAS__ mutations are known to
β¦ LIBER β¦
741 CLINICAL SIGNIFICANCE OF BRAF AND KRAS MUTATIONS IN PROSTATE CANCER
β Scribed by S. Choi; J.M. Chung
- Book ID
- 119621463
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 163 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1569-9056
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
BRAF and KRAS mutations in prostatic ade
β
Nam-Yun Cho; Minhee Choi; Baek-Hee Kim; Yong-Mee Cho; Kyung Chul Moon; Gyeong Ho
π
Article
π
2006
π
John Wiley and Sons
π
French
β 356 KB
BRAF and KRAS mutations in stomach cance
β
Lee, Sug Hyung; Lee, Jong Woo; Soung, Young Hwa; Kim, Hong Sug; Park, Won Sang;
π
Article
π
2003
π
Nature Publishing Group
π
English
β 141 KB
KRAS and BRAF mutations in sinonasal can
β
Fernando LΓ³pez; Cristina GarcΓa InclΓ‘n; Jhudit PΓ©rez-Escuredo; CΓ©sar Γlvarez Mar
π
Article
π
2012
π
Elsevier Science
π
English
β 460 KB
KRAS and BRAF mutations in prostate carc
β
Yanying Shen; Yachao Lu; Xiaolu Yin; Guanshan Zhu; Jianshan Zhu
π
Article
π
2010
π
Elsevier Science
π
English
β 234 KB
The expression and clinical significance
β
Zhihong Wen; Xiaoli Zou; Guang Yang; Hui Wang
π
Article
π
2011
π
Springer
π
English
β 295 KB
Frequency of KRAS, BRAF, and NRAS mutati
β
Cecily P. Vaughn; Scott D. ZoBell; Larissa V. Furtado; Christine L. Baker; Wade
π
Article
π
2011
π
John Wiley and Sons
π
English
β 85 KB
π 1 views
## Abstract Mutational analysis of __KRAS__ codons 12 and 13 is standard for patients with metastatic colorectal cancer since mutations in these codons predict lack of response to antiβEGFR therapies. However, even among patients whose tumors are wildtype for __KRAS__ codons 12 and 13, only a subse