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BRAF and KRAS mutations in stomach cancer

✍ Scribed by Lee, Sug Hyung; Lee, Jong Woo; Soung, Young Hwa; Kim, Hong Sug; Park, Won Sang; Kim, Su Young; Lee, Jong Heun; Park, Jik Young; Cho, Yong Gu; Kim, Chang Jae

Book ID
110067839
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
141 KB
Volume
22
Category
Article
ISSN
0950-9232

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## Dear Sir, The RAS proteins participate in the RAS-RAF-MEK-ERK-MAPKinase pathway, which mediates cellular responses to growth signals. 1 There are 3 RAF genes, each encoding cytoplasmic serine/threonine kinases that are regulated by binding to RAS. 1,2 We have recently reported that BRAF is soma