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668 P53 Mutation and chemosensitivity in breast cancer patients

✍ Scribed by A. Makris; T.J. Powles; C. Allred; M. Dowsett

Book ID: 116167414
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 146 KB
Volume: 31
Category: Article
ISSN: 0959-8049
DOI: 10.1016/0959-8049(95)95917-u

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The cause of Li-Fraumeni syndrome, a rare group syndrome of familial cancers, has recently been identified. Patients with this inherited condition are highly susceptible to specific neoplasms, including early-onset breast cancers. The available evidence links Li-Fraumeni syndrome to inherited mutati