p53and chemosensitivity in bladder cancer
β Scribed by Hiroyuki Nishiyama; Jun Watanabe; Osamu Ogawa
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 316 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1341-9625
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π SIMILAR VOLUMES
## Abstract There are increasing reports showing the clinical significance of the __p53__ polymorphism status in terms of the response to chemotherapy. We investigated whether __p53__ polymorphism and mutation were associated with __in vitro__ sensitivity to 5βfluorouracil (5βFU) in patients with c
## BACKGROUND. Although p53 gene mutation frequently is observed in ovarian carcinoma, the function of the p53 gene in chemosensitivity has not been defined conclusively. The objective of the current study was to elucidate the relation between chemotherapy-induced apoptosis through the p53 pathway