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526 Cancer-associated fibroblasts desensitizes head and neck squamous cell carcinoma cells to epidermal growth factor receptor-targeted therapy

✍ Scribed by A. Johansson; A. Ansell; A. Östman; K. Roberg

Book ID
119602307
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
47 KB
Volume
8
Category
Article
ISSN
1359-6349

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✍ Mark E. Sharafinski; Robert L. Ferris; Soldano Ferrone; Jennifer R. Grandis 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 382 KB 👁 2 views

## Abstract ## Background Cumulative evidence implicates the epidermal growth factor receptor (EGFR) as an important therapeutic target in head and neck squamous cell carcinoma (HNSCC). The basis for the lack of correlation between EGFR expression in the HNSCC tumor and clinical responses to EGFR