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52. Synthesis and adrenocortical conversion of 20β-hydroperoxycholest-5-en-3β-ol-22-one

✍ Scribed by J.E. Van Lier; M. Milot


Book ID
118924690
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
132 KB
Volume
5
Category
Article
ISSN
0022-4731

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The readily accessible pregna-5,16-dien-3/l-ol-20-one ( I ) was transformed into 3/l-acetoxy-pregna-5,I7-dien-20-isopropoxy-16one ( 9). This compound was labelled by base-catalyzed isotopic exchange and then reconverted into labelled pregna-5,16-dien-3/l-01-20-one (13). Hydrogenation of this last on