5-Chloropyrazole-4-carbaldehydes as synthons for intramolecular 1,3-dipolar cycloadditions
✍ Scribed by L'abb�, Gerrit; Emmers, Sabine; Dehaen, Wim; Dyall, Leonard K.
- Book ID
- 120052955
- Publisher
- Royal Society of Chemistry
- Year
- 1994
- Weight
- 889 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1472-7781
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## Abstract magnified image The title compound 2‐butyl‐5‐chloro‐3__H__‐imidazole‐4‐carbaldehyde was transformed into tricyclic heterocycles by substituting the chlorine atom by an unsaturated thiolate or alkoxide and then converting aldehyde function into 1,3‐dipole. Chloramine‐T was used as an ef
## Abstract magnified image A number of aldimines have been obtained in very good yield in reaction of 5‐formyl‐1,3‐dimethyluracil with various substituted anilines in boiling methanol. Selected aldimines were treated with nitrile oxides generated from 4‐chlorobenzaldoxime or 4‐methylbenzaldoxime f