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4β-[(4-Alkyl)-1,2,3-triazol-1-yl] podophyllotoxins as anticancer compounds: Design, synthesis and biological evaluation

✍ Scribed by Doma Mahendhar Reddy; Jada Srinivas; Gousia Chashoo; Ajit K. Saxena; H.M. Sampath Kumar

Book ID
108116566
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
737 KB
Volume
46
Category
Article
ISSN
0223-5234

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ChemInform Abstract: 4β-[(4-Alkyl)-1,2,3
ChemInform Abstract: 4β-[(4-Alkyl)-1,2,3-triazol-1-yl] Podophyllotoxins as Anticancer Compounds: Design, Synthesis and Biological Evaluation.
✍ Doma Mahendhar Reddy; Jada Srinivas; Gousia Chashoo; Ajit K. Saxena; H. M. Sampa 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 38 KB 👁 1 views

## Abstract The title compounds (III) are evaluated for their cytotoxicity against the human cancer cell lines SF‐295, A‐549, PC‐3, Hep‐2, HCT‐15 and MCF‐7.

Synthesis and Biological Evaluation of 4
Synthesis and Biological Evaluation of 4β-[(4-Substituted)-1,2,3-triazol-1-yl]podophyllotoxins as Potential Anticancer Agents
✍ Pitta Bhaskar Reddy; Satyam Kumar Agrawal; Swaran Singh; Bilal A. Bhat; Ajit K. 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 206 KB 👁 1 views

## Abstract A series of novel 4__β__‐[(4‐substituted)‐1,2,3‐triazol‐1‐yl]podophyllotoxin derivatives were synthesized by employing Cu^I^‐catalyzed click chemistry and evaluated for their anticancer activity against a panel of seven human cancer cell lines (HT‐29, HCT‐15, 502713, HOP‐62, A‐549, MCF‐

Design, Synthesis, and Biological Testin
Design, Synthesis, and Biological Testing of 4β-[(4-Substituted)-1,2,3-triazol-1-yl]podophyllotoxin Analogues as Antitumor Agents
✍ Pitta B. Reddy; David V. Paul; Satyam K. Agrawal; Ajit K. Saxena; Halmuthur M. S 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 495 KB 👁 1 views

## Abstract A series of 4β‐[(4‐substituted)‐1,2,3‐triazol‐1‐yl]podophyllotoxin analogues have been synthesized with high regio‐selectivity by employing copper(I)‐catalyzed 1,3‐dipolar cycloaddition of 1‐__O__‐propargyl monosaccharides with C4β‐azido podophyllotoxin and C4β‐azido‐4′‐__O__‐demethyl p

ChemInform Abstract: Design, Synthesis,
ChemInform Abstract: Design, Synthesis, and Biological Testing of 4β-[(4-Substituted)-1,2,3-triazol-1-yl]podophyllotoxin Analogues as Antitumor Agents.
✍ Pitta B. Reddy; David V. Paul; Satyam K. Agrawal; Ajit K. Saxena; Halmuthur M. S 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 30 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v