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48 Variety of presenilin-1 mutations in japanese familial early-onset Alzheimer's disease

โœ Scribed by K. Kaminot; Y. Nishiwaki; A. Yoshiiwa; M. Takeda; S. Sato; Y. Sakaki; K. Ii; T. Miki; T. Ogihara


Book ID
117413802
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
141 KB
Volume
17
Category
Article
ISSN
0197-4580

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Very early-onset familial Alzheimer's di
โœ Jill S. Goldman; Bruce Reed; Rosalie Gearhart; Joel H. Kramer; Bruce L. Miller ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 47 KB ๐Ÿ‘ 1 views

## Background: Early-onset familial alzheimer's disease (eofad) is linked to mutations in three autosomal dominant genes: ps1, ps2 and app. the clinical presentation and age of onset of mutations is variable. ## Objectives: The aim of this report is to describe a novel ps1 mutation believed to be