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Alteration in Brain Presenilin 1 mRNA Expression in Early Onset Familial Alzheimer's Disease

โœ Scribed by Amanda J.L. Barton; Barry W. Crook; Eric H. Karran; Frank Brown; Deborah Dewar; David M.A. Mann; R.Carl A. Pearson; David I. Graham; John Hardy; Mike Hutton; Karen Duff; Alison M. Goate; Robert F. Clark; Gareth W. Roberts

Book ID
118769242
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
184 KB
Volume
5
Category
Article
ISSN
1055-8330

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โœ Jill S. Goldman; Bruce Reed; Rosalie Gearhart; Joel H. Kramer; Bruce L. Miller ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 47 KB ๐Ÿ‘ 1 views

## Background: Early-onset familial alzheimer's disease (eofad) is linked to mutations in three autosomal dominant genes: ps1, ps2 and app. the clinical presentation and age of onset of mutations is variable. ## Objectives: The aim of this report is to describe a novel ps1 mutation believed to be