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Three different mutations of presenilin 1 gene in early-onset Alzheimer's disease families

✍ Scribed by Kouzin Kamino; Shinji Sato; Yoshiyuki Sakaki; Aoi Yoshiiwa; Yumiko Nishiwaki; Masatoshi Takeda; Hirotaka Tanabe; Tsuyoshi Nishimura; Kunio Ii; Peter H. St George-Hyslop; Tetsuro Miki; Toshio Ogihara


Book ID
116125606
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
304 KB
Volume
208
Category
Article
ISSN
0304-3940

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Very early-onset familial Alzheimer's di
✍ Jill S. Goldman; Bruce Reed; Rosalie Gearhart; Joel H. Kramer; Bruce L. Miller πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 47 KB πŸ‘ 1 views

## Background: Early-onset familial alzheimer's disease (eofad) is linked to mutations in three autosomal dominant genes: ps1, ps2 and app. the clinical presentation and age of onset of mutations is variable. ## Objectives: The aim of this report is to describe a novel ps1 mutation believed to be