ฮฑ-Mercaptoacyl dipeptides that inhibit a
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Shripad S. Bhagwat; Cynthia A. Fink; Candido Gude; Kenneth Chan; Ying Qiao; Yumi
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Article
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1995
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Elsevier Science
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English
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ct-Mercaptoaeyl dipoptides were prepared and found to inhibit angiotensin converting enzyme (ACE) and neutral endopeptidase 24.11 (NEP). Compounds with a proline as the C-terminal amino acid, and possessing the S-stereochemistry at the thiol bearing carbon were preferred for optimal ACE inhibition w