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3,5-Bis(arylidene)piperid-4-ones Containing 1,3,2-Oxazaphosphorinane Moieties: Synthesis and Antitumor Activity

✍ Scribed by Shipov, Anatolii E.; Makarov, Mikhail V.; Petrovskii, Pavel V.; Rybalkina, Ekaterina Yu.; Nelyubina, Yulia V.; Odinets, Irina L.


Book ID
120292669
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
313 KB
Volume
24
Category
Article
ISSN
1042-7163

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N-phosphorylated 3,5-bis(arylidene)4-pip
✍ Irina L. Odinets; Oleg I. Artyushin; Evgenii I. Goryunov; Konstantin A. Lyssenko πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 123 KB πŸ‘ 1 views

In a search for cytotoxic fluorescent ma- terials, a series of N-phosphorylated compounds 2a-c were prepared by phosphorylation of 3,5-bis(4-N,Ndimethylbenzylidene)-4-piperidone 1. According to X-ray investigations, molecule 2a is E,E-isomer with axial position of the P(O)(OCH 2 CF 3 ) 2 substituent