Synthesis, characterization and structure–activity relationship of novel N-phosphorylated E,E-3,5-bis(thienylidene)piperid-4-ones
✍ Scribed by Michael V. Makarov; Evgeniya S. Leonova; Ekaterina Yu. Rybalkina; Paul Tongwa; Victor N. Khrustalev; Tatiana V. Timofeeva; Irina L. Odinets
- Book ID
- 118435732
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- French
- Weight
- 575 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0223-5234
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In a search for cytotoxic fluorescent ma- terials, a series of N-phosphorylated compounds 2a-c were prepared by phosphorylation of 3,5-bis(4-N,Ndimethylbenzylidene)-4-piperidone 1. According to X-ray investigations, molecule 2a is E,E-isomer with axial position of the P(O)(OCH 2 CF 3 ) 2 substituent
## Abstract magnified image Twenty‐four novel tetramic acid derivatives (__Z__)‐3‐((__E__)‐1‐(alkyloxyimino)ethyl)‐5‐arylidene‐4‐hydroxypyrroline‐2‐ones **6a**, **6b**, **6c**, **6d**, **6e**, **6f**, **6g**, **6h**, **6i**, **6j**, **6k**, **6l**, **6m**, **6n**, **6o**, **6p**, **6q**, **6r**, **