3,4-Dihydro-4-hydroxy-1,3-benzoxazin-2-one derivatives
β Scribed by R. E. Strube; F. A. Mackellar
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 272 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0165-0513
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IJ Some 1,4-dihydre2H-3,1-benzoxa~in-2-one derivatives were synthesized and tested for pharmacological activity. CPhenyl-6-chloro-l,4-dihydro-2H-3,l-benzoxazin-2-one (Compound 4) exhibited anticonvulsant activity against chemically and electrically induced seizures and low acute toxicity in mice. St
The Preparation of 2-Hydroxyethyl-2,3-dihydro-2H-1,4-benzoxazin-3(4H)-one Derivatives. -An effective strategy for the preparation of the title compounds (III), important intermediates in the synthesis of a series of novel antibacterial agents, is described. -(FRECHETTE, R. F.; BEACH,