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3.048 UNDERSTANDING MOLECULAR MECHANISMS UNDERLYING LEUCINE-RICH REPEAT KINASE 2 (LRRK2)-RELATED PARKINSON'S DISEASE (PD)

✍ Scribed by H. Liu; P.W. Ho; J.W. Ho; D.B. Ramsden; Z. Zhou; S.-L. Ho


Book ID
117755151
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
75 KB
Volume
18
Category
Article
ISSN
1353-8020

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Leucine-rich repeat kinase 2 (LRRK2): A
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## Abstract Parkinson's disease (PD) is the most common neurodegenerative movement disorder, with a prevalence of more than 1% after the age of 65 years. Mutations in the gene encoding leucine‐rich repeat kinase‐2 (__LRRK2__) have recently been linked to autosomal dominant, late‐onset PD that is cl