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Genetic characteristics of leucine-rich repeat kinase 2 (LRRK2) associated Parkinson’s disease

✍ Scribed by Soraya Bardien; Suzanne Lesage; Alexis Brice; Jonathan Carr


Book ID
116820880
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
497 KB
Volume
17
Category
Article
ISSN
1353-8020

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Leucine-rich repeat kinase 2 (LRRK2): A
✍ Payal N. Gandhi; Shu G. Chen; Amy L. Wilson-Delfosse 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 209 KB

## Abstract Parkinson's disease (PD) is the most common neurodegenerative movement disorder, with a prevalence of more than 1% after the age of 65 years. Mutations in the gene encoding leucine‐rich repeat kinase‐2 (__LRRK2__) have recently been linked to autosomal dominant, late‐onset PD that is cl