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Leucine-rich repeat kinase 2 (LRRK2) as a potential therapeutic target in Parkinson's disease

✍ Scribed by Byoung Dae Lee; Valina L. Dawson; Ted M. Dawson


Book ID
116919106
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
487 KB
Volume
33
Category
Article
ISSN
0165-6147

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Leucine-rich repeat kinase 2 (LRRK2): A
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## Abstract Parkinson's disease (PD) is the most common neurodegenerative movement disorder, with a prevalence of more than 1% after the age of 65 years. Mutations in the gene encoding leucine‐rich repeat kinase‐2 (__LRRK2__) have recently been linked to autosomal dominant, late‐onset PD that is cl