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Development of Inducible Leucine-rich Repeat Kinase 2 (LRRK2) Cell Lines for Therapeutics Development in Parkinson’s Disease

✍ Scribed by Huang, Liang; Shimoji, Mika; Wang, Juan; Shah, Salim; Kamila, Sukanta; Biehl, Edward R.; Lim, Seung; Chang, Allison; Maguire-Zeiss, Kathleen A.; Su, Xiaomin; Federoff, Howard J.


Book ID
120835924
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
703 KB
Volume
10
Category
Article
ISSN
1933-7213

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Leucine-rich repeat kinase 2 (LRRK2): A
✍ Payal N. Gandhi; Shu G. Chen; Amy L. Wilson-Delfosse 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 209 KB

## Abstract Parkinson's disease (PD) is the most common neurodegenerative movement disorder, with a prevalence of more than 1% after the age of 65 years. Mutations in the gene encoding leucine‐rich repeat kinase‐2 (__LRRK2__) have recently been linked to autosomal dominant, late‐onset PD that is cl